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The main role of Xdh was to act as a catalyst for the conversion of hypoxanthine to xanthine, and ultimately to uric acid [81]

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Taken together, the structural plasticity of a partially folded state is hypothesized to be an intrinsic property of the NTD that allows interactions with many structurally diverse binding partners 32,35 , such as coactivators of the P160 family 36 , the basal transcription factors TATA-box binding protein and transcription factor IIF 37 , and intramolecular interactions with the LBD

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