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A Review of the Literature and Guide for Primary Care Physicians

DSIP administration did not significantly affect corticotropin-releasing-hormone (CRH)-stimulated or meal-induced ACTH and cortisol secretion, indicating thatcontrary to stress-protective effects reported in some animal studiesDSIP does not measurably blunt the human cortisol response

And because there are trillions of chemical reactions occurring at any given time within our body, we can literally get a minute-by-minute or even second-by-second snapshot of how our metabolism is running

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Similarly, pH-sensitive optical probes have been used to map extracellular acidification associated with increased glycolytic flux and poor vascular perfusion (185, 186)