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Charley horse crampsthe sudden, violent contraction of the entire calfare the extreme version, often occurring at night during passive foot extension

Treatment with Reclast resulted in a 6.7% increase in BMD at the lumbar spine, 6.0% at the total hip, and 5.1% at the femoral neck, over 3 years as compared to placebo

Choudhry MN, et al

It is supplied in a 100 tabs/bottle format designed for convenient handling in research environments.

Then theres the fact that vitamin B12 is not naturally present in any plant foods, so if you follow a vegetarian, vegan, or mostly plant-based diet, you may simply not be getting enough