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Long-term use of metformin, a drug commonly prescribed for type 2 diabetes, is strongly associated with vitamin B12 deficiency and lower folic acid levels as it can block absorption, which may lead to increased homocysteine levels and risk for cardiovascular disease

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The team mitigated potential issues by planning work with minimal disruption, restoring all affected features and using trenchless methodssuch as pipe bursting and cured-in-place liningfor over 90% of replacements