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For example, a modified-release dosage of doxycycline 40 mg may have comparable efficacy with traditional doxycycline 100 mg given once daily, or a solubilized gel formation of BPO may also enhance bioavailability, follicular penetration, and efficacy

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The mechanism that renders the recycling pathway sensitive to glucose starvation remains incompletely understood

Wan et al (135) found that induction of AMPK phosphorylation in chondrocytes enhances its stability and activity and that activation of the AMPK/Nrf2/HO-1 pathway attenuates ferroptosis, offering a potential therapeutic strategy for arthritis

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