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Stabilization of phosphofructokinase 1 platelet isoform by AKT promotes tumorigenesis

Therefore, lipid peroxidation is exacerbated by the presence of intracellular iron while GPX4 suppression diminishes the detoxification of lipid peroxides generated in response to increasing intracellular ROS content

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8890 Polymeric NPs can encapsulate a wide range of therapeutic agents, including small molecules, proteins, and nucleic acids

All these data suggest that circadian clock components also affect tumor escape mechanisms and, therefore, could be responsible for the induction of cold tumors and the failure for current immunotherapies