glutathione peroxidase 3 protein

glutathione peroxidase 3 protein induced mitochondria-mediated apoptosis via AMPK /ERK1/2 pathway and resisted autophagy-related ferroptosis via AMPK/mTOR pathway in hyperplastic prostate | Journal of Translational Medicine International Journal of Oncology

Name: glutathione peroxidase 3 protein induced mitochondria-mediated apoptosis via AMPK /ERK1/2 pathway and resisted autophagy-related ferroptosis via AMPK/mTOR pathway in hyperplastic prostate | Journal of Translational Medicine International Journal of Oncology
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International Journal of Oncology Glutathione Peroxidase 3 (GPX3) (NM_002084) Human Tagged ORF Clone Glutathione peroxidase Wikipedia Glutathione Peroxidase 3 an overview ScienceDirect Topics Unglycosylated recombinant human glutathione peroxidase 3 mutant from Escherichia coli is active as a monomer Scientific Reports

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Nature 373 , 427432 (1995)

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This system significantly contributes to the overall antioxidant capability of cells

doi: 10.1186/s12986-017-0200-8

Current strategies address these through catalytic inhibition (e.g., MLN4924 targeting NEDD8-activation [73]), allosteric modulation (e.g., -elemene disrupting OTUB1-GPX4 binding [79]), and epigenetic reprogramming (e.g., OTUD4 demethylation to restore ATM signaling [97])