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The physicochemical profiling of this subset, including computational and experimental solubility assessments, as well as reactivity profiling against cysteine surrogates and the validation through differential scanning fluorimetry (DSF) screening against c-Jun N-terminal kinase 3 (JNK3), ubiquitin-specific protease 7 (USP7), and the tumor suppressor p53 core domain followed by intact protein mass spectrometry, was published previously by our group

This review explores the relevant mechanisms of TCM compound prescriptions, TCM botanical drugs, and active compounds in the prevention and treatment of DACC in recent years