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This deficiency creates a cycle: low glutathione leads to more oxidative stress, which leads to more skin reactivity, which further depletes glutathione

12 , e2409344 (2025)

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Full-length transcript sequences were aligned to the reference genome (ASM1485139v1) with alignment rates exceeding 99% across all tissues, yielding 10 million high-confidence transcripts for male tissues (testis and muscle) and 8 million for female ovarian tissue, thereby establishing a robust dataset for isoform-level analyses (Table 1)

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