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While its hard to generalize about effects, Piomelli notes that for a person in their 20s to 40s, weighing anywhere from 50-80kg (110-175lbs), 10-20mg of THC per serving would be enough to produce a noticeable buzz definitely enough to cause a full-blown high for someone who isnt a regular user. I always say: know before you go, says Harvard neuroscientist Staci Gruber, who directs the longest-running study of medical cannabis use in the United States

Many smokers prefer to roll their own because it allows them to personalize their experiencechoosing the type of tobacco, the amount, and the filter (if any)