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6.4 Solid lipid nanoparticles SLNs are submicron-sized particles of solid lipids that could encapsulate lipophilic and hydrophilic drugs (Figure 10)

It was found that Cinobufacini significantly reduced the number of M1 macrophages and increased the number of M2 macrophages, and inhibited the polarization of M1 macrophages in lipopolysaccharide-induced RAW 264.7 cells

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an effect which ultimately leads to increases in muscle protein synthesis

GSH depletion and GPX4 inhibition cause enhancement of oxidative stress, which are key drivers (Li et al