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Six clinical trials involving over 900 participants established this window through systematic dose-finding studies

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To investigate whether follicular VEGF expression directly promotes hair growth and vascularization, we studied the hair cycle in transgenic mice with selective overexpression of VEGF in basal epidermal keratinocytes and in outer root sheath keratinocytes of hair follicles, targeted by a keratin 14 promoter cassette (17)

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