Technique Ultrasound-guided approach (preferred) Local Corticosteroid Injection at tendon sheath under Ultrasound guidance (see Shoulder Ultrasound) Approached in-plane to linear Ultrasound probe (probe short axis to anterior Shoulder - home position) Do not inject within tendon (and avoid circumflex artery within groove) Technique Landmark-based approach Images Landmarks Identify bicipital tendon in bicipital groove (proximal Humerus) Mark point of maximal tenderness over groove Injected with sterile technique (with Betadine preparation of skin) Direct needle parallel to bicipital groove (vertically oriented) Needle enters skin at 30 degrees oriented superiorly Do not inject bicipital tendon Infiltrate area around groove, but not into tendon Flow resisted when needle is inside tendon Withdraw needle slightly and retry Continue to withdraw until not in tendon Complications Bicipital tendon rupture Associated with intratendinous injection Do not inject bicipital tendon References
Sermorelin injections can be administered by subcutaneous (SubQ) or intramuscular (IM) injection, depending on your prescribers direction
Abnormal mitochondrial fission results in mitochondrial fragmentation, triggering depolarization, oxidative stress, and ultimately severe neuronal damage (Santos et al., 2015
While we anticipate retatrutide being a strong option for many people seeking weight loss, it may be particularly useful for anyone who falls into one or more of these categories: Didnt respond to earlier GLP-1 drugs like Wegovy, Ozempic, Rybelsus, Liraglutide, Zepbound, Mounjaro, etc Plateaued with other GLP-1s but still havent met your target weight Have a large body percentage of weight to lose (20% or more) Retatrutide is currently undergoing clinical trials necessary for it to obtain FDA approval (which is anticipated by summer) , so it's not yet available to be prescribed
Some users prefer alternating between the injured area and an abdominal site to reduce local tissue stress while maintaining systemic levels
