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Weeks 9 through 12 Total weight loss from a 4 to 6mg Retatrutide protocol over this period often lands in the 15 to 25 lb range depending on starting weight, protocol adherence, and diet quality

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Dominari, A., et al

Preliminary data suggests that retatrutide could lead to more weight loss than semaglutide or tirzepatide because it targets more receptors involved in suppressing appetite and lowering blood sugar

But it is essential to read it for what it is: computational and in-vitro gene-signature analysis, not evidence that injecting GHK-Cu produces a measurable, beneficial, whole-body genomic reset in living humans, and certainly not evidence that such a reset visibly improves skin