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In summary, artesunate acts by reducing M1 macrophage activation and suppressing the RIPK1/RIPK3/MLKL signaling cascade through the downregulation of Mincle expression, thereby diminishing the inflammatory response and necroptosis, which contributes to improvement of renal injury in AKI

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Clinical supervision remains essential to mitigate these risks

The four broad categories of activities are matched to the four functional domains of the brain outlined by Dr