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Elevated expression of cPLA2 has been observed in IS patients, correlating with increased severity of injury and infarct size (Cui et al., 2021)

doi: 10.1074/jbc.M112.405050 15 CaoSSKaufmanRJ

10.1016/j.ijcard.2016.12.053 Int J Cardiol

ROS, the products of normal cellular metabolism attack PUFAs causing peroxidation of lipids (LPO) and generate MDA which is an important and sensitive marker of peroxidative damage 47