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In response to oxidative stress, mitochondrial DNA (mtDNA) is highly susceptible to damage due to its proximity to the ETC, lack of protective histones, and inefficient DNA repair mechanisms

This is exemplified by variable responsiveness to therapeutics such as those targeting IL-23/IL-17 signalling, and other consistently observed differences in clinical course including progression and severity both within and between SpAs subtypes

The mode of intracellular self-digestion identified as autophagy breaks down and recycles intracellular components by encasing intracellular material in autophagic vesicles and fusing with lysosomes (Li et al., 2023)

Dies unterstreicht die Effektivitt des technologischen Ansatzes bei der Bereitstellung essenzieller Antioxidantien

Particularly, I look at HLA, or human leukocyte antigens