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Clonal analysis of immunodominance and cross-reactivity of the CD4 T cell response to SARS-CoV-2

However, through the discovery of many genetic associations outside of the HLA complex over the past decade, it has become increasingly clear that HLA-B27 is not the sole genetic determinant of the disease, with many variants across the genome now known to contribute to AS susceptibility [4, 5]

Interestingly, the female steady-state is low for S near 1 and also low for S = 3.31, but at intermediate values of S , the female steady-state is considerably higher than that the male's

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