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Novel screening assay for in vivo selection of Klebsiella pneumoniae genes promoting gastrointestinal colonisation

Owing to the increase in the demand for GFs, various expression systems, including Escherichia coli [1, 15,16,17,18,19], Bacillus subtilis [20], mammalian cell [21], baculovirus [22], silkworm [23, 24], and plant [11, 12] systems, are used for cost-effective and efficient production of recombinant GFs

The Path Forward If future trials establish safety and clear clinical benefit in humans under standard drug development pathways, the regulatory landscape could change

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For the control of AF rate and rhythm, iron chelation therapy can effectively alleviate arrhythmia (119, 200)