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No significant difference was observed in gene expression of markers for cardiac dysfunction or hypertrophy, such as Nppb and Acta1 among all treatment groups (Supplemental Figure 7)

5-on/2-off weekly pattern: Use DSIP Sunday through Thursday nights Take Friday and Saturday off Continue indefinitely with monthly full-week breaks This approach maintains consistent sleep support on work nights while allowing regular receptor recovery

Protective Effect of Resveratrol against Ischemia-Reperfusion Injury via Enhanced High Energy Compounds and eNOS-SIRT1 Expression in Type 2 Diabetic Female Rat Heart