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Thus, dosing regimens for treatment of acute disease may need to be altered to account for the slight but possibly important differences in pharmacokinetics between cats and humans

Ju J, Picinich SC, Yang Z, Zhao Y, Suh N, Kong AN, Yang CS: Cancer-preventive activities of tocopherols and tocotrienols

A medication requiring hepatic metabolism is not automatically a toxin, and the metabolic pathway differs according to the compound, dose, genetics, nutrition, liver function and drug interactions