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Three-dimensional scanning, modeling, and printing have all been used in the assessment and treatment of pectus excavatum and carinatum

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The core 3D structures targets were obtained from the Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB) ( The 3D structures of compounds were uploaded to Discovery Studio (2019) for pre-processing of the small molecule

The lack of full overlapping between the three-melanocyte lineage-specific markers suggests differential labelling of melanocyte populations

Unless indicated otherwise, cystine-free medium was prepared by supplementing cystine-, methionine- and glutamine-free DMEM (Gibco, CA, USA) with 100 M methionine, 4 mM glutamine, 1 mM sodium pyruvate, 0.2% bovine serum albumin (BSA), 100 U/ml penicillin and 100 g/ml streptomycin