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Environ Toxicol Pharmacol 39:683689 Chung L-C, Chiang K-C, Feng T-H, Chang K-S, Chuang S-T, Chen Y-J, Tsui K-H, Lee J-C, Juang H-H (2017) Caffeic acid phenethyl ester upregulates N-myc downstream regulated gene 1 via ERK pathway to inhibit human oral cancer cell growth in vitro and in vivo

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GHK-Cu is a naturally occurring copper-binding tripeptide (Gly-His-Lys) shown in laboratory and small clinical studies to support collagen synthesis, wound healing and antioxidant defenses

Owing to their high oxygen consumption, skeletal muscle fibers are inherently prone to ROS generation during contraction and metabolism ( Elevated ROS also activate the NF-B pathway by depleting glutathione (GSH), downregulating myogenic transcription factors (MyoD, MyoG), and upregulating the transcriptional repressor Yin Yang 1 (YY1), thereby impairing myogenic differentiation (Xiang et al., 2022)