nature glutathione gpx review GPx1 deficiency confers increased susceptibility to ferroptosis in macrophages from individuals with active Crohn's disease Glutathione peroxidase 3 is a

doi: 10.1016/j.biopha.2023.116021 Summary Keywords hepatocellular carcinoma, tumor microenvironment, metabolism reprogram, signaling pathways, immune evasion Citation Yang H, Li J, Niu Y, Zhou T, Zhang P, Liu Y and Li Y (2025) Interactions between the metabolic reprogramming of liver cancer and tumor microenvironment

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This regulatory effect was further validated in human hepatocyte cell line LO2, where similar increases in LDLR surface expression and LDL uptake were observed (Fig

Therefore, the prevention of primary liver cancer is urgent