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Moreover, intersections between upregulated DEGs in the control group and downregulated DEGs in the treatment groups, as well as between downregulated DEGs in the control group and upregulated DEGs in the treatment groups, also demonstrated that the combination group had a greater overlap with the control group than either single-drug group did (Additional file 2: Figure S5)

[DOI] [PubMed] [Google Scholar] 40.Hsieh M-J, Lee C-H, Chueh H-Y, Chang G-J, Huang H-Y, Lin Y, et al

TGF and matrix-regulated epithelial to mesenchymal transition

Adv Exp Med Biol 1:5976 Hope M, Saxby T (2007) Tendon healing

Older individuals often have reduced nitric oxide production, stiffer blood vessels, and altered responses to vasoactive compounds