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Shindo Y, Witt E, Han D, Epstein W, Packer L

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Quick Answer Medicare Coverage Requirements: Chronic low back pain lasting 6+ months Failed conservative treatment (at least 3 different approaches for 6+ months) MRI showing Modic Type 1 or Type 2 changes in vertebrae L3-S1 Patient must be 18+ years old (skeletally mature) Cannot have severe spinal stenosis, active infection, or osteoporosis Limited to once per vertebral body, lifetime maximum of 4 treatments Chronic low back pain affects nearly 80% of adults at some point in their lives, with about 20% developing chronic pain lasting 12 weeks or longer

Autocrine antiapoptotic stimulation of cultured adult T-cell leukemia cells by overexpression of the chemokine I-309

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