glutathione peroxidase ulcerative colitis Levels of lipid (LPO), reduced (GSH), catalase Advances and prospects of microenvironment-targeted

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In FAO, acyl-CoA moieties are conjugated to carnitine by the enzyme carnitine palmitoyltransferase 1A (CPT1A), with subsequent transport of acylcarnitine species across the mitochondrial membrane by carnitine acylcarnitine translocase (CACT) in exchange for a free carnitine molecule, a process referred to as the carnitine shuttle. Next, the intramitochondrial enzyme, carnitine palmitoyltransferase 2 (CPT2), decouples the acylcarnitine back to a long-chain acyl-CoA (LC-acyl-CoA) species (32), freeing carnitine to be transported back to the cytosol

BAP1 links metabolic regulation of ferroptosis to tumour suppression

Ann Neurol 79:929939