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However, the time taken will depend on the severity of the disorder and the specific nutrients being administered

Typical GSH-GSSG ratios measured in whole tissue extracts (of the order of 1020) point to redox potentials closer to 2200 mV, which would mean that glutathione and NADP(H) potentials are signicantly removed from equilibrium (Fig

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To that purpose, like most holdases, CnoX transfers its substrates to ATP-dependent foldases ( E

Acknowledgements This work was funded by the Motor Neurone Disease Association and the MRC-MRF, grant numbers Hasnain/Apr15/833-791 and MRF-060-0002-RG-HASNA, respectively, awarded to S.S.H., S.V.A., & G.S.A.W