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Important caveat: the evidence for these mechanisms and benefits is preclinical based on cell and animal studies

Mice lacking one of the alleles of the COQ7 gene ( mCOQ7/mCLK1 gene ) show extended longevity even though their CoQ levels are the same as wild-type mice, suggesting that a factor other than CoQ per se may be responsible for lifespan extension in these animals (Lapointe and Hekimi, 2008)

Biomacromol 19:28412848

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