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10.1016/j.cmi.2023.04.006 123

Environmental pollutant exposure (as discussed in section 4.9) contributes to adipose dysfunction through multiple mechanisms

Chest Med

To further validate the findings, in vivo experiments were conducted using a mouse model of type 2 DN

This regulation is achieved through Akt substrate of 160kDa (AS160) that produces cellular responses to both Akt and mTORC2 signals to regulate glucose transporter 4 (GLUT4) trafficking during insulin stimulation, and to maintain glucose homeostasis (161)