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To move Epitalon from experimental to evidence-based, several developments are essential: Randomized, double-blind, placebo-controlled clinical trials, ideally targeting specific endpoints (sleep, immune aging, telomere attrition) Toxicology and long-term safety studies, including exploration of stereoisomer effects and off-target consequences Validated delivery systems (e.g., dendrimer-conjugates, transdermal patches) that make real-world use feasible Pharmacodynamic biomarkers, to identify responders and track efficacy objectively over time Epitalon is not snake oil, but its also not a magic bullet

It has also demonstrated the potential to reduce inflammation, improve gut health, and even accelerate recovery from surgery or injury

bioRxiv2024 November 22

This was achieved using the Matlab scripts given in the supplementary software of the Tsigkinopoulou et al protocol

Furthermore, like EHD methods, microfluidic processes are typically carried out under mild, ambient conditions, which helps avoid degrading heat-sensitive compounds