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When administering novel probiotic functional foods for treating GIT problems, the antigenicity level of the diet should be considered

Application of this assay to analyze plasma from patients with known oxidative stress (sickle cell disease and sepsis) and from a patient with sickle cell disease treated with the antioxidant N-acetylcysteine suggests that cysteine disulfides, in particular protein-bound cysteine, serve as sensitive plasma biomarkers for the extent of oxidative stress and effectiveness of antioxidant treatment

For this reason, antihistamines are mainly used in acute or severe cases, or when it is not possible to follow a low-histamine diet [8], or when the administration of drugs that may release histamine is unavoidable [93]

Importantly, we found HLA-B, HLA-E, and PSMB10 all related to antigen presentation to be enriched among down-regulated genes in tumours with high LEF-1 expression ( Figure 8 , Table 1 ) suggesting an adverse impact of Wnt/-catenin pathway on tumour recognition by immune cells