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it exerts multifaceted effects on host health, including maintaining intestinal barrier integrity, regulating immune responses, and modulating metabolic processes (Melndez-Oliva et al., 2025)

Severe depression or active suicidal thoughts The MHRA, FDA, and EMA have reviewed the evidence and found no causal link between GLP-1 medications and suicidal thoughts or behaviour

Therefore, the focus was on therapeutic interventions published between January 2010 and November 2023, overlapping with the period of increasing IMF exposure

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