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It should be noted, however, that H2 blockers like famotidine tend to exhibit a phenomenon known as tachyphylaxis, where the medication tends to lose its effectiveness over time. Adverse effects reported in the use of gastroesophageal reflux disease treatments in children: A 10 year literature review, British Journal of Clinical Pharmacology Famotidine, Epocrates Famotidine drug summary, Prescribers Digital Reference Famotidine tablets prescribing information, U.S

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