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World J Surg Oncol 54:27 Tokumoto M, Lee J-Y, Shimada A, Tohyama C, Satoh M (2018) Glutathione has a more important role than metallothionein-I/II against inorganic mercury-induced acute renal toxicity

The article also notes that research findings remain mixed and highlights the need for continued studies to better understand their complex mechanisms

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Metabolic effects have been observed in other in vitro systems including: renal cortex tubules (Michoudet & Baverel, 1985: altered pyruvate/lactate metabolism), kidney, and muscle microsomal preparations (Cederbaum & Rubin, 1977: inhibition of pyruvate dehydrogenase), perfused hearts and cardiac whole homogenates (Schreiber et al., 1972, 1974: myocardial protein synthesis and inhibition of cardiac microsomal protein synthesis