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While high levels of homocysteine may not cause joint pain, they can cause an increased risk of cardiovascular disease, an increased risk of cognitive disorders such as Alzheimers disease, and an increased risk of fractures

This could explain why some users report such dramatic improvements even in chronic injuries that had been resistant to other treatments

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By far, the most common cause in this category is type 1 hemochromatosis related to mutations of the HFE gene, typically homozygous C282Y/C282Y or compound heterozygous C282Y/H63D