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Focusing on dynamic associations between metabolism and disease stages, longitudinal metabolomic cohort studies can track changes in metabolic profiles of patients from early asymptomatic stages to stable and acute exacerbation phasesidentifying core metabolic characteristics at different disease stages and addressing gaps in the current understanding of correlations between disease staging and metabolic abnormalities

However, enhancing FSP1 activity may be detrimental to GBM treatment strategies, as FSP1 counteracts ferroptosis

Dotzauer, D

Furthermore, it is also possible that DMSO acts as a methyl donor to induce hypermethylation 31

[12] Song D, et al