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To summarize, the emergence of high blood pressure in patients with MetS is a multi-step process involving a variety of pathophysiological pathways (141)

2079-A NASH CIRRHOSIS: DISTINCT PHENOTYPICAL DIFFERENCES, MORE SYSTEMIC INFLAMMATION, AND MORE FRAIL THAN VIRAL-RELATED CIRRHOSIS Yu JUN Wong 1,2 , Heng Yi Tan 3 , Siew Yoon Yap 4 , Geraldine Lim 4 , Seok Hwee Khoo 4 , Jessica Tan 1 , Rahul Kumar 1,2 , Joan Khoo 5 , Rosario Helen Barbara 6 and Paul Edward Hutchinson 3 , (1)Department of Gastroenterology & Hepatology, Changi General Hospital, (2)Duke-Nus Medical School, Singhealth, (3)Flow Cytometry Laboratory, Life Sciences Institute, National University of Singapore, (4)Clinical Trial Research Unit, Changi General Hospital, (5)Department of Endocrinology, Changi General Hospital, (6)Department of Geriatric Medicine, Changi General Hospital Background: NASH is replacing viral hepatitis as the fastest-growing etiology of liver cirrhosis globally with limited therapeutic options

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Biochemical basis of oxidative protein folding in the endoplasmic reticulum