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Several studies evaluating turmerics effectiveness (curcumin) in iron overload have shown reductions in ALT and AST liver enzymes, along with a marker called NTBI (Non-Transferrin Bound Iron)

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While a moderate concentration of ROS is critical for eggsperm fusion, and fertilization, excessive ROS generation is primarily related to telomere shortening, sperm DNA fragmentation, and alterations in the methylation pattern leading to male infertility