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Conclusions Although challenges associated with some of these compounds remain, important advances have been made in the development of safer and more effective drugs that could actually represent a breakthrough for fatal degenerative diseases such as ALS

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Polyunsaturated fatty acids and gene expression in mammalian systems

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Results FAP-specific activation of promellitin-modified liposomes (PRL) PRL and various other liposome formulations, including plain PEGylated liposomes (PL), maleimide-activated PEGylated liposome (ML), scrambled cys-promelittin peptide-tagged liposomes (SCL) and promelittin-mimicking fluorescence-quenched peptide-tagged liposomes (FQL) are schematically depicted in Fig