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Rentera, The polymodal ion channel transient receptor potential vanilloid 4 modulates calcium flux, spiking rate, and apoptosis of mouse retinal ganglion cells

Exceeding the normal intracellular concentration of cysteine due to its recovery from cystine or blocking export is also dangerous for the cell, as it causes an increase in ROS, and also activates the Fenton genotoxic reaction [2, 4]

10.1016/j.jnutbio.2022.108972 201 ShimadaK.SkoutaR.KaplanA.YangW

Treatment by folates and betaine combined with a low-methionine diet is effective in vitamin B 6 nonresponders (Franken et al, 1994)

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