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In vivo combinational therapy of MRTX0902, trametinib and anti-PD-1 antibodies The c-MYC-lucOS OE /Tp53 KO /Kras HCC mouse model was induced in C57BL/6 mice via HTVI, as described previously

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CpG island hypermethylation and tumor suppressor genes: a booming present, a brighter future

A mixed model for repeated measurements was used to input any missing data from test subjects that discontinued treatment or required a dose of rescue medication