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Methylglyoxal (MG) is a highly reactive -oxoaldehyde that is primarily generated intracellularly through the spontaneous degradation of glycolytic triose phosphate intermediates, namely dihydroxyacetone phosphate and glyceraldehyde 3-phosphate

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This evidence strongly implies that ER stress and ROS could reciprocally activate each other under chronic IH conditions

Single-cell transcriptome analysis indicates fatty acid metabolism-mediated metastasis and immunosuppression in male breast cancer