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The idea originated from the work of Otto Warburg and colleaguesfirst published in the 1920swho noticed the propensity for cancer cells to consume increased quantities of glucose (1, 2)

J Exp Med 192:17311744 Mattiasson G, Sullivan PG (2006) The emerging functions of UCP2 in health disease and therapeutics

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The review also encompasses targeted therapeutic strategies for the ferroptosis pathway and provides an evaluation of the potential and latest research trends surrounding these treatment methods in dermatological disease therapy