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Interestingly, another study mentioned the key role of GPX4 in preventing ferroptosis in activated T cells (155)

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RCTs deliver high internal validity by isolating treatment effects under controlled conditions, while RWE offers external validity by capturing outcomes across diverse patient populations and real-world practice

However, we found that apoptosis-associated protein changes were not significant after knockdown of SPI1 in ccRCC (Fig

Pei Z, Deng K, Xu C, Zhang S (2023) The molecular regulatory mechanisms of meiotic arrest and resumption in oocyte development and maturation