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The information regarding drug-drug interactions includes the following updates: Methotrexate may decrease serum valproate levels and potentially result in increased frequency of seizures or bipolar symptoms

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When DEGs were cross-referenced to a metabolic gene list (2,921 genes) compiled from previously published studies 6,32 , we observed significant overrepresentation of metabolic DEGs, as determined by Fishers exact test (Extended Data Fig

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