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Subcutaneous administration in normal and metabolically dysregulated mice significantly inhibits NNMT activity in metabolically active tissues (adipose, liver, muscle), increases systemic NAD+ levels, enhances mitochondrial function, and improves energy metabolism

10.1093/hmg/ddu328 12 GhumanS.Van HemelrijckM.GarmoH.HolmbergL.MalmstrmH.LambeM.et al (2017)

10.1038/s41586-019-1705-2 14 BurtonL

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