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If the dose threshold is reached at the beginning of the specified irradiation, then the subsequent responses are dose-independent (within a certain range)

If a pharmaceutical company will be supplying the drug, but will not itself be submitting the IND, the company is not the sponsor

Injection of preclinical meningiomas with 8803 induces survival benefits, including in an immunocompetent orthotopic setting, through remodeling of the tumor microenvironment, immune infiltration, and downregulation of tumor-mediated immune suppression, thereby nominating 8803 for treatment consideration in meningiomas