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The genetic literature directly supports a non-specific etiological role for glutamatergic dysfunction

Oiso, N., Fukai, K., Kawada, A

Abstract: Female FVB/N HER2/neu transgenic mice from the age of 2 months were subcutaneously injected with saline, the peptide Epitalon (AlaGluAspGly) or with the peptide Vilon (LysGlu) in a single dose of 1 g/mouse for 5 consecutive days every month

For instance, for a collective of 24 neurologically healthy sample donors, a good, age-consistent BBB-integrity value of albumin quotient ( Q HSA ) of 5.25 10 3 , but higher Q -values for GPX ( Q GPX = 8.31 10 3 ) and TXNRD ( Q TXNRD = 21.34 10 3 ) were observed, demonstrating active transport into the brain-CSF compartment (Solovyev et al., 2013)

Heavy Oxidative-stress Exposure Patients managing high oxidative load from lifestyle or chronic stress