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It has been documented that BP from a corn tree ( Quercus acutissima ) is reported as an excellent antioxidant and anti-melanogenesis agent due to the presence of high amount of phenolic acids, and its possible mode of action is the obstruction of melanin-producing enzyme (tyrosinase) ( On the other hand, free phenolics are digestible in the small intestine while bound phenolic compounds are not absorbed (in the small intestine) and reached in the large intestine where they pass the fermentation process (by colon microbiota) and liberate bound phenolic compounds

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Swisher S , Ajani J, Komaki R, Putnam J, Walsh G, Liao Z, Yao J, Faust J, Wu TT, Roth J, Study Group MER

A recent proteomics-based study has revealed that NNMT is a main metabolic regulator of CAFs in ovary cancer (74)

Clin Colon Rectal Surg 29(3):185195